This drug is a combination of two antihistamines, pyrilamine and chlorpheniramine , and a decongestant, phenylephrine. Triotann-S is used to treat symptoms associated with the common cold and hay fever , such as runny nose, itchy eyes, and sneezing.
Common brand names:AllerTan, Nalax A 12, Triotann-S Pediatric
Summary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
Reduce Side Effects
Laboratory studies have shown that compounds found in Panax ginseng enhance the ability of phenylephrine to constrict blood vessels. Controlled studies are necessary to determine whether taking Panax ginseng at the same time as phenylephrine will enhance the beneficial effects of the drug.The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Potential Negative Interaction
Antihistamines, including chlorpheniramine, can cause "anticholinergic" side effects such as dryness of mouth and heart palpitations. Henbane (Hyoscyamus niger) also has anticholinergic activity and side effects. Therefore, use of henbane with chlorpheniramine could increase the risk of anticholinergic side effects, though apparently no interactions have yet been reported. Henbane should not be taken except by prescription from a physician trained in its use, as it is extremely toxic.The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Many drugs used in the treatment of high blood pressure cause relaxation or dilation of blood vessels. Laboratory studies show that emodin, a compound in Polygonum multiflorum, also relaxes blood vessels. However, animal studies reveal that phenylephrine blocks the action of emodin. Controlled studies are needed to determine whether Polygonum multiflorum helps people with high blood pressure and whether phenylephrine blocks its beneficial effects.The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
- Top of the page
Last Review: 03-18-2015
Copyright © 2019 Healthnotes, Inc. All rights reserved. www.healthnotes.com
Please read the disclaimer about the limitations of the information provided here. Do NOT rely solely on the information in this article. The Healthnotes knowledgebase does not contain every possible interaction.
The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2019.