Vitamin B2Skip to the navigation
Vitamin B2 is a water-soluble vitamin needed to process amino acids and fats, activate vitamin B6 and folic acid , and help convert carbohydrates into the fuel the body runs on-adenosine triphosphate (ATP). Under some conditions, vitamin B2 can act as an antioxidant .
What Are Star Ratings?
Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
3 Stars Reliable and relatively consistent scientific data showing a substantial health benefit.
2 Stars Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
1 Star For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
This supplement has been used in connection with the following health conditions:
How It Works
How to Use It
The ideal level of intake is not known. The amounts found in many multivitamin supplements (20-25 mg) are more than adequate for most people.
Where to Find It
Dairy products, eggs, and meat contain significant amounts of vitamin B2. Leafy green vegetables, whole grains, and enriched grains contain some vitamin B2.
Vitamin B2 deficiency can occur in alcoholics . Also, a deficiency may be more likely in people with cataracts 1 , 2 or sickle cell anemia .3 In developing countries, vitamin B2 deficiency has been found to be a risk factor for the development of preeclampsia in pregnant women.4 People with chronic fatigue syndrome may be deficient in vitamin B2.5
Best Form to Take
Riboflavin is the most commonly used supplement form of vitamin B2 and most clinical trials have used that form. The biologically active form of vitamin B2-riboflavin 5'-phosphate-is also commercially available, although most of it is converted into riboflavin in the intestine before being absorbed.6
Interactions with Supplements, Foods, & Other Compounds
Interactions with Medicines
Certain medicines interact with this supplement.
Types of interactions: Beneficial Adverse Check
Replenish Depleted Nutrients
Reduce Side Effects
Potential Negative Interaction
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers' package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a supplement with your doctor or pharmacist.
1. Bhat KS. Nutritional status of thiamine, riboflavin and pyridoxine in cataract patients. Nutr Rep Internat 1987;36:685-92.
2. Prchal JT, Conrad ME, Skalka HW. Association of presenile cataracts with heterozygosity for galactosaemic states and with riboflavin deficiency. Lancet 1978; 1:12-3.
3. Varma RN, Mankad VN, Phelps DD, et al. Depressed erythrocyte glutathione reductase activity in sickle cell disease. Am J Clin Nutr 1983;38:884-7.
4. Wacker J, Fruhauf J, Schulz M, et al. Riboflavin deficiency and preeclampsia. Obstet Gynecol 2000;96:38-44.
5. Heap LC, Peters TJ, Wessely S. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med 1999;92:183-5.
6. Gaby, AR. Nutritional Medicine. Concord, NH: Fritz Perlberg Publishing, 2011.
Last Review: 05-24-2015
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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2017.
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