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oprelvekin (injection)Skip to the navigationPronunciation: oh PERL ve kin Brand: Neumega What is the most important information I should know about oprelvekin?Stop using oprelvekin and get emergency medical help if you have any of these signs of an allergic reaction: fever, rash, shortness of breath, chest pain, wheezing, confusion, fainting, hives, or swelling of your face, lips, tongue, or throat. Once you have had an allergic reaction to oprelvekin, you must never use it again. Other serious side effects of oprelvekin include swelling or rapid weight gain, chest pain, uneven heartbeats, sudden numbness or weakness, confusion, problems with speech or balance, and sudden vision loss or pain behind your eyes. Call your doctor at once if you have any of these side effects. What is oprelvekin?Oprelvekin is a protein that stimulates production of platelets in the blood. Platelets are important for proper clotting of the blood and for wound healing. Oprelvekin is used to prevent platelets from becoming dangerously low in certain people receiving chemotherapy that can result in bone marrow suppression or the need for blood platelet transfusions. Oprelvekin may also be used for purposes not listed in this medication guide. What should I discuss with my healthcare provider before using oprelvekin?You should not use oprelvekin if you are allergic to it. To make sure oprelvekin is safe for you, tell your doctor if you have:
FDA pregnancy category C. It is not known whether oprelvekin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine. It is not known whether oprelvekin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. How should I use oprelvekin?Oprelvekin is injected under the skin. You may be shown how to use injections at home. Do not self inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes. Treatment with oprelvekin is usually started 6 to 24 hours after chemotherapy is completed. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Oprelvekin is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine. Do not shake the medication bottle or you may ruin the medicine. Prepare your dose only when you are ready to give an injection. Do not use if the medicine has changed colors or has particles in it. Call your pharmacist for new medicine. Use a different place on your stomach, thigh, hip, or upper arm each time you give the injection. Your care provider will show you the best places on your body to inject the medication. Do not inject into the same place two times in a row. Each single-use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose. Use a disposable needle only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets. It may take up to 21 days of using this medicine before your platelets increase. For best results, keep using the medication as directed. While using oprelvekin, you may need frequent blood tests. Store unused oprelvekin vials and diluent syringes in the refrigerator. Do not freeze. What happens if I overdose?Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while using oprelvekin?Avoid making any changes in your diet while using this medication. Oprelvekin can cause fluid retention and swelling. Your doctor may recommend a low-salt diet to prevent this condition. What are the possible side effects of oprelvekin?Get emergency medical help if you have any of these signs of an allergic reaction:
An allergic reaction may occur even if you have received oprelvekin in the past without a reaction. Once you have had an allergic reaction to oprelvekin, you must never use it again. Stop using oprelvekin and call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect oprelvekin?Other drugs may interact with oprelvekin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
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